Oncogene Analysis

Fusion Detection from RNA-seq Data

Consensus fusion calling on existing RNA-seq data. No sample shipment: you provide FASTQ or BAM files, we return a per-sample fusion report with breakpoints, partner genes, reading frame and database status. Standard pipelines report the known fusions and leave the remainder unprocessed -- this analysis starts there.

Direct

About this service

PlatformArriba + STAR-Fusion

Data provided

Per-sample fusion report as PDF plus the complete hit list as TSV.
Cohort overview across all samples of an order, highlighting recurrent events.
Raw output of both callers and an alignment QC report.
For plausibly novel fusions, a separate section with the information required for functional characterisation.

Workflow

Data access via the Atlas portal or a transfer route you provide; datasets we delivered ourselves can be used directly.
Alignment against GRCh38 or the reference of your choice, retaining chimeric alignments for fusion detection.
Fusion detection with two independent callers and formation of a consensus; single-caller hits are reported separately.
Per-hit annotation: breakpoint at exon and base level, partner gene, reading frame, retained functional domains, number of supporting reads.
Comparison against COSMIC, the Mitelman database and known artefact lists; classification as known, plausibly novel or likely artefact.

Configure

Your order

Sample count

Between 1 and 1000 samples

Use case (optional)

Notes (optional)

Catalogue